Numb Protects Renal Proximal Tubular Cells from Puromycin Aminonucleoside-Induced Apoptosis through Inhibiting Notch Signaling Pathway

Numb was originally discovered as an intrinsic cell fate determinant in Drosophila by antagonizing Notch signaling.The present study is to characterize the role of Numb in oxidative stress-induced apoptosis of renal proximal tubular cells.Exposure of NRK52E cells to puromycin aminonucleoside (PA) resulted in caspase 3-dependent apoptosis.Numb expre

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The Beginnings of the Merchants University of Bilbao (1481-1511). Corporation of Occupational Representation and Port Government Institution

It is known the importance of mercantile corporations in the increment of medieval naval commerce.However, the analysis of the Merchants University of Bilbao, the largest Cantabrian port of pre-industrial Castile, has been relegated due to lack of documentation.But, Indoor Socks thanks to the discovery of new sources, very abundant and of great doc

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